Cristiano Ronaldo became the first man to score 50 goals in Serie A, La Liga and the Premier League as his double against Lazio put Juventus on the brink of the Serie A title.
Ronaldo opened the scoring with a penalty and tapped in a second from Paulo Dybala’s pass.
Juve are eight points clear of Inter Milan and need four points to clinch a ninth consecutive title.
Ciro Immobile scored a penalty to pull one back for fourth-placed Lazio.
Ronaldo and Immobile are joint top scorers in Serie A with 30 goals each.
Juventus XI: Ronaldo, Bonucci, Szczesny, Cuadrado, Douglas Costa, Ramsey, Sandro, Dybala, Rabiot, Bentancur, De Ligt
Subs: Buffon, Matuidi, Higuain, Pjanic, Danilo, Pinsoglio, Rugani, Demiral, M. Olivieri, L. Zanimacchia, Simone Muratore, Wesley
Lazio XI: Caicedo, Immobile, Parolo, Acerbi, D. Anderson, Strakosha, Bastos, Lazzari, Cataldi, Milinkovic-Savic, Luiz Felipe
Subs: Proto, Guerrieri, Vavro, N. Armini, A. Anderson, Adekanye, Raul Moro, L. Falbo